Meropenem

Antibiotics

Meropenem
  • Brand logo & Packshot - Mepecon™ 500 mg / Mepecon™ 1000 mg.
  • Composition - Each vial contains Sterile Meropenem IP Eq. to Anhydrous Meropenem 500 mg / 1000 mg.
  • Description - Meropenem is a broad-spectrum carbapenem antibiotic. The bactericidal activity of Meropenem results from the inhibition of cell wall synthesis. Meropenem readily penetrates the cell wall of most Gram-positive and Gram-negative bacteria to reach penicillin-binding-protein (PBP) targets.
  • Indications & Usage - Meropenem I.V. is indicated for the treatment of the following infections in adults and children above 3 months of age, when caused by susceptible bacteria: Pneumonia, including community-acquired pneumonia and nosocomial pneumonia; Complicated urinary tract infections; Complicated intra-abdominal infections; Intra- and post-partum infections; Complicated skin and skin structure infections; Broncho-pulmonary infections in cystic fibrosis; Acute bacterial meningitis. Meropenem I.V. may be used in the management of neutropenic patients with fever that is suspected to be due to a bacterial infection. Meropenem has been found to be effective in eliminating concurrent bacteraemia in association with bacterial meningitis.
  • Dosage & administration - The recommended dose of Meropenem for pneumonia, including community-acquired pneumonia and nosocomial pneumonia; complicated urinary tract infection; complicated intra-abdominal infections; intra-and post-partum infections and complicated skin and skin structure infections is 500 mg or 1 gm to be administrated every 8 hourly. For broncho-pulmonary infections in cystic fibrosis and acute bacterial meningitis, it is 2 gm every 8 hourly. For the management of febrile neutropenic patients, the recommended dose is 1 gm every 8 hourly.
  • Storage conditions - Freshly prepared solutions of Meropenem should be used whenever possible. However, constituted solutions of Meropenem maintain satisfactory potency at controlled room temperature 15-25°C (59-77°F) or under refrigeration at 4°C. Solutions of intravenous Meropenem should not be frozen.